pentobarbital decreases amounts of ponatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Avoid Until the coadministration outweighs the feasible possibility of ponatinib underexposure; monitor for signs of diminished efficacy.
Keep track of Intently (2)pentobarbital will decrease the extent or result of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Strong CYP3A4 inducers may well lower suvorexant efficacy; if amplified suvorexant dose essential, do not exceed twenty mg/day
pentobarbital will decrease the level or result of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will minimize the extent or result of pimavanserin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Avoid coadministration if at all possible. Watch for diminished pimavanserin efficacy. An increase in pimavanserin dosage could be required.
pentobarbital will lower the level or influence of cariprazine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Keep track of get more info Closely (1)pentobarbital will reduce the level or impact of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or influence of carbamazepine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Keep track of Intently (1)pentobarbital will minimize the extent or impact of mifepristone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers have not been examined, coadministration not advisable by manufacturer
pentobarbital will minimize the extent or result of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Powerful CYP3A4 inducers may well decrease suvorexant efficacy; if enhanced suvorexant dose required, tend not to exceed twenty mg/working day
pentobarbital will minimize the level or effect of cevimeline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known.
pentobarbital will reduce the extent or outcome of buprenorphine buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will lower the extent or impact of parecoxib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.
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pentobarbital will reduce the extent or impact of tamoxifen by influencing hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep track of.